Systemic and Pulmonary Vascular Dysfunction in Children Conceived by Assisted Reproductive Technologies

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Vascular Medicine Systemic and Pulmonary Vascular Dysfunction in Children Conceived by Assisted Reproductive Technologies

Background—Assisted reproductive technology (ART) involves the manipulation of early embryos at a time when they may be particularly vulnerable to external disturbances. Environmental influences during the embryonic and fetal development influence the individual’s susceptibility to cardiovascular disease, raising concerns about the potential consequences of ART on the long-term health of the of...

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Systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies.

BACKGROUND Assisted reproductive technology (ART) involves the manipulation of early embryos at a time when they may be particularly vulnerable to external disturbances. Environmental influences during the embryonic and fetal development influence the individual's susceptibility to cardiovascular disease, raising concerns about the potential consequences of ART on the long-term health of the of...

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Letter by Phillips and O'Leary regarding article, "systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies".

I read with interest the article by Scherrer et al. This research was largely advertised in a Swiss television show, 36.9, on April 4, 2012. In this show, it was clearly evident that children conceived by assisted reproduction techniques were informed of the hypothesis of the study before the measurements, that they were at risk to be victims of heart infarction at a very young age, and that th...

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Cardiovascular dysfunction in children conceived by assisted reproductive technologies.

Epidemiological studies demonstrate a relationship between pathological events during foetal development and future cardiovascular risk and the term 'foetal programming of cardiovascular disease' has been coined to describe this phenomenon. The use of assisted reproductive technologies (ARTs) is growing exponentially and 2-5% of children are now born by this procedure. Emerging evidence indicat...

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Right ventricular dysfunction in children and adolescents conceived by assisted reproductive technologies.

Assisted reproductive technologies (ART) predispose the offspring to vascular dysfunction, arterial hypertension, and hypoxic pulmonary hypertension. Recently, cardiac remodeling and dysfunction during fetal and early postnatal life have been reported in offspring of ART, but it is not known whether these cardiac alterations persist later in life and whether confounding factors contribute to th...

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ژورنال

عنوان ژورنال: Circulation

سال: 2012

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.111.071183